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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (D's) » Dronabinol


Dronabinol is a cannabinoid designated chemically as (6aR-trans)-6a,7,8,10a-tetrahydro-
6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol. Dronabinol has the following empirical formula:

C21H30O2 (molecular weight = 314.47)

Dronabinol, delta-9-tetrahydrocannabinol (delta-9-THC), is naturally-occurring and has been extracted from Cannabis sativa L. (marijuana).

Dronabinol is also chemically synthesized and is a light-yellow resinous oil that is sticky at room temperature and hardens upon refrigeration. Dronabinol is insoluble in water and is formulated in sesame oil. It has a pKa of 10.6 and an octanol-water partition coefficient: 6,000:1 at pH 7.

Capsules for oral administration: Marinol is supplied as round, soft gelatin capsules containing either 2.5 mg, 5 mg, or 10 mg dronabinol. Each Marinol capsule is formulated with the following inactive ingredients: sesame oil, gelatin, glycerin, methylparaben, propylparaben, FD&C Yellow No. 6 (5 mg and 10 mg), and titanium dioxide.

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