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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Fexofenadine



DESCRIPTION

Fexofenadine HCl is a histamine H1-receptor antagonist with the chemical name (±)-4-[1-hydroxy-4-[4(hydroxydiphenylmethyl)-l¾piperidinyl]¾butyl]-a,dimethyl benzeneacetic acid hydrochloride. The molecular weight is 538.13 and the empirical formula is C32H39NO4·HCl. Fexofenadine HCl is a white to off-white crystalline powder. It is freely soluble in methanol and ethanol, slightly soluble in chloroform and water, and insoluble in hexane. Fexofenadine HCl is a racemate and exists as a zwitterion in aqueous media at a physiological pH.

Allegra is formulated as capsules for oral administration. Each capsule contains 60 mg fexofenadine HCl and the following excipients: croscarmellose sodium, gelatin, lactose, microcrystalline cellulose, and pregelatinized starch. The printed capsule shell is made from gelatin, iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide, and other ingredients.

CATEGORIES, BRAND NAMES

CATEGORIES: Rhinitis, seasonal allergic; Pregnancy Category C; FDA Approved 1996 Jul; Top 200 Drugs

FDA Drug Classes: Antihistamines

BRAND NAMES:

BRAND NAMES: Allegra; Telfast; Telfast BD
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Telfast (Australia; France; Germany; Hong-Kong; New-Zealand; Thailand)
Telfast BD (Indonesia)





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