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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Fexofenadine


Fexofenadine HCl is a histamine H1-receptor antagonist with the chemical name (±)-4-[1-hydroxy-4-[4(hydroxydiphenylmethyl)-l¾piperidinyl]¾butyl]-a,dimethyl benzeneacetic acid hydrochloride. The molecular weight is 538.13 and the empirical formula is C32H39NO4·HCl. Fexofenadine HCl is a white to off-white crystalline powder. It is freely soluble in methanol and ethanol, slightly soluble in chloroform and water, and insoluble in hexane. Fexofenadine HCl is a racemate and exists as a zwitterion in aqueous media at a physiological pH.

Allegra is formulated as capsules for oral administration. Each capsule contains 60 mg fexofenadine HCl and the following excipients: croscarmellose sodium, gelatin, lactose, microcrystalline cellulose, and pregelatinized starch. The printed capsule shell is made from gelatin, iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide, and other ingredients.


CATEGORIES: Rhinitis, seasonal allergic; Pregnancy Category C; FDA Approved 1996 Jul; Top 200 Drugs

FDA Drug Classes: Antihistamines


BRAND NAMES: Allegra; Telfast; Telfast BD
(Foreign Brand names outside U.S. in italics)

Telfast (Australia; France; Germany; Hong-Kong; New-Zealand; Thailand)
Telfast BD (Indonesia)

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