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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Fluoxetine



DESCRIPTION

Fluoxetine hydrochloride is an antidepressant for oral administration; it is chemically unrelated to tricyclic, tetracyclic, or other available antidepressant agents. It is designated (±)-N-methyl-3-phenyl-3-[(a,a,a-trifluoro-p-tolyl)-oxy]propylamine hydrochloride and has the empirical formula of C17H18F3NOHCl. Its molecular weight is 345.79.

Fluoxetine hydrochloride is a white to off-white crystalline solid with a solubility of 14 mg/ml in water.

Each Prozac Pulvule contains fluoxetine hydrochloride equivalent to 10 mg (32.3 mmol), 20 mg (64.7 mmol), or 40 mg (129.3 mmol) of fluoxetine. The Pulvules also contain starch, gelatin, silicone, titanium dioxide, iron dioxide, and other inactive ingredients. The 10 mg and 20 mg Pulvules also contain FD&C blue no. 1, and the 40 mg Pulvule also contains FD&C blue no. 1 and FD&C yellow no. 6.

Each Prozac tablet contains fluoxetine HCl equivalent to 10 mg (32.3 mmol) of fluoxetine. The tablets also contain microcrystalline cellulose, magnesium stearate, crospovidone, hydroxypropyl methylcellulose, titanium dioxide, polyethylene glycol, and yellow iron oxide. In addition to the above ingredients, the 10 mg tablet contains FD&C blue no. 1 aluminum lake, and polysorbate 80.

The oral solution contains fluoxetine hydrochloride equivalent to 20 mg/5 ml (64.7 mmol) of fluoxetine. It also contains alcohol 0.23%, benzoic acid, flavoring agent, glycerin, purified water, and sucrose.

CATEGORIES, BRAND NAMES

CATEGORIES: Bulimia nervosa; Depression; Obsessive-compulsive disorder; Pregnancy Category B; FDA Approved 1987 Dec; Top 200 Drugs; Orphan Drugs

FDA Drug Classes: Antidepressants

BRAND NAMES:

BRAND NAMES: Adofen; Affectine; Alzac 20; Ansilan; Deproxin; Erocap; Fluctin; Fluctine; Fludac; Flufran; Flunil; Fluoxac; Fluoxeren; Fluoxil; Fluox-Puren; Flutin; Flutine; Fluxen; Fluxil; Fontex; Foxetin; Lorien; Lovan; Margrilan; Modipran; Neupax; Nopres; Nuzak; Oxedep; Pragmaten; Prizma; Proctin; Prodep; Prozac; Prozac 20; Rowexetina; Sanzur; Sinzac; Zactin; Zepax
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Adofen (Spain)
Affectine (Israel)
Alzac 20 (Guatemala)
Ansilan (Colombia)
Deproxin (Thailand)
Erocap (Australia)
Fluctin (Germany)
Fluctine (Austria; Switzerland)
Fludac (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Flufran (India)
Flunil (India)
Fluoxac (Mexico)
Fluoxeren (Italy)
Fluoxil (Dominican-Republic)
Fluox-Puren (Germany)
Flutin (Colombia)
Flutine (Israel; Thailand)
Fluxen (Taiwan)
Fluxil (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Fontex (Denmark; Finland; Norway; Sweden)
Foxetin (Korea)
Lorien (South-Africa)
Lovan (Australia)
Margrilan (Hong-Kong; Thailand)
Modipran (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Neupax (Peru)
Nopres (Indonesia)
Nuzak (South-Africa)
Oxedep (India)
Pragmaten (Ecuador)
Prizma (Israel)
Proctin (Korea)
Prodep (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Prozac 20 (Korea; Malaysia; Mexico; Philippines; Taiwan; Thailand)
Rowexetina (Costa-Rica; Dominican-Republic; El-Salvador; Guatemala; Honduras; Nicaragua; Panama)
Sanzur (South-Africa)
Sinzac (Taiwan)
Zactin (Australia; Taiwan)
Zepax (Colombia)

COST OF THERAPY: $237.60 (Depression; Prozac Capsule; 20 mg; 1/day; 90 days)





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