Gemfibrozil

DESCRIPTION

Gemfibrozil is a lipid regulating agent. It is available as tablets for oral administration.

Each tablet contains 600 mg gemfibrozil. Each also contains calcium stearate; candelilla wax FCC; microcrystalline cellulose; hydroxypropyl cellulose; hydroxypropyl methylcellulose, USP; methylparaben, NF; Opaspray white; polyethylene glycol; polysorbate 80; propylparaben; colloidal silicon dioxide; pregelatinized starch. The chemical name is 5- (2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid.

The empirical formula is C₁₅H₂₂O₃ and the molecular weight is 250.35; the solubility in water and acid is 0.0019% and in dilute base it is greater than 1%. The melting point is 58°-61°C. Gemfibrozil is a white solid which is stable under ordinary conditions.

CATEGORIES, BRAND NAMES

CATEGORIES: Hypercholesterolemia; Hyperlipidemia; Hyperlipoproteinemia; Hypertriglyceridemia; Pregnancy Category B; FDA Approved 1986 Nov; Top 200 Drugs

FDA Drug Classes: Hyperlipidemia

BRAND NAMES:

BRAND NAMES: Apo-Gemfibrozil; Ausgem; Bolutol; Brozil; Cholespid; Clearol; Decrelip; Elmogan; Fetinor; Fibratol; Fibrocit; Gemd; Gemfibril; Gemfibromax; Gemlipid; Gemnpid; Gempar; Gem-S; Gevilon; Gevilon Uno; Gozid; Hidil; Hipolixan; Ipolipid; Jezil; Lanaterom; Lifibron; Lipazil; Lipigem; Lipira; Lipizyl; Lipur; Lopid; Low-Lip; Normolip; Polyxit; Progemzal; Reducel; Regulip; Synbrozil; Tripid; Zilop
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Apo-Gemfibrozil (New-Zealand)
Ausgem (Australia)
Bolutol (Spain)
Brozil (Malaysia)
Cholespid (Philippines)
Clearol (Taiwan)
Decrelip (Spain)
Elmogan (Hong-Kong)
Fetinor (Indonesia)
Fibratol (Peru)
Fibrocit (Italy)
Gemd (Taiwan)
Gemfibril (Thailand)
Gemfibromax (Australia)
Gemlipid (Italy; Turkey)
Gemnpid (Taiwan)
Gem-S (Taiwan)
Gevilon (Czech-Republic; Finland; Germany; Hungary; Poland; Switzerland)
Gevilon Uno (Germany)
Gozid (Thailand)
Hidil (Thailand)
Hipolixan (Ecuador; Peru)
Ipolipid (Bahamas; Bahrain; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Curacao; Cyprus; Egypt; Ethiopia; Gambia; Ghana; Guinea; Guyana; Hong-Kong; Iran; Iraq; Israel; Ivory-Coast; Jamaica; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Malaysia; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Niger; Nigeria; Oman; Puerto-Rico; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Surinam; Syria; Tanzania; Thailand; Trinidad; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Jezil (Australia; New-Zealand)
Lanaterom (Indonesia)
Lifibron (Indonesia)
Lipazil (Australia)
Lipigem (India; Philippines)
Lipira (Indonesia)
Lipizyl (India)
Lipur (France)
Low-Lip (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Normolip (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; India; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Polyxit (Thailand)
Progemzal (Indonesia)
Reducel (Philippines)
Regulip (Bahrain; Benin; Burkina-Faso; Cyprus; Egypt; Ethiopia; Gambia; Ghana; Guinea; Iran; Iraq; Israel; Ivory-Coast; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Syria; Tanzania; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Synbrozil (Hong-Kong)
Zilop (Colombia; Indonesia)

COST OF THERAPY: $1022.00 (Hyperlipidemia; Lopid Tablet; 600 mg; 2/day; 365 days)

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