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You are here: Home » Products Listed by Brand » McKesson Products » Drug Reference (A's) » Azatadine and Pseudoephedrine


TRINALIN® brand of azatadine maleate, USP and pseudoephedrine sulfate, USP
Long- Acting Antihistamine/ Decongestant

TRINALIN Long-Acting Antihistamine/ Decongestant REPETABS (brand of repeat-action tablets) Tablets contain 1 mg azatadine maleate, USP in the tablet coating and 120 mg pseudoephedrine sulfate, USP, equally distributed between the tablet coating and the barrier-coated core. Following ingestion, the two active components in the coating are quickly liberated; release of the decongestant in the core is delayed for several hours.

Azatadine maleate is an antihistamine having the empirical formula, C20H22N2 2C4H4O4, and chemical name, 6,11-Dihydro-11-(-methyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta [1,2-b]pyridine maleate (1:2). The molecular weight of azatadine maleate is 522.54.

Azatadine maleate is a white to off-white powder and is very soluble in water and soluble in alcohol.

Pseudoephedrine sulfate, a sympathomimetic amine, is a salt of pseudoephedrine, one of the naturally occurring alkaloids obtained from various species of the plant Ephedra. The empirical formula for pseudoephedrine sulfate is (C10H15NO)2 H2SO4; and the chemical name is Benzenemethanol, -[1-(methylamino)ethyl]-,[S-( R*, R*)]-,sulfate (2:1) (salt). The molecular weight of pseudoephedrine sulfate is 428.56.

It is a white to off-white crystal or powder, very soluble in water, freely soluble in alcohol, and sparingly soluble in chloroform.

The inactive ingredients for TRINALIN REPETABS Tablets are: acacia, butylparaben, calcium sulfate, carnauba wax, corn starch, D&C Red No. 30 Al Lake, FD&C Yellow No. 6 Al Lake, gelatin, lactose, magnesium stearate, neutral soap, oleic acid, povidone, rosin, sugar, talc, white wax, and zein.

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