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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (B's) » Butalbital Compound With Codeine


Butalbital Compound With Codeine (butalbital, aspirin, caffeine, and codeine phosphate) is supplied in capsule form for oral administration. Each capsule contains:

  • codeine phosphate, USP 30 mg (1/2 gr) Warning: May be habit forming.
  • butalbital, USP 50 mg Warning: May be habit forming.
  • caffeine, USP 40 mg
  • aspirin, USP 325 mg

Codeine phosphate occurs as fine, white, needle-shaped crystals, or white, crystalline powder. It is affected by light. Its chemical name is 7,8-didehydro 4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol phosphate (1:1) (salt) hemihydrate.

Butalbital, 5-allyl-5-isobutyl-barbituric acid, a white odorless crystalline powder, is a short- to intermediate-acting barbiturate. Its molecular weight is 224.26 and its empirical formula is C11H16N2O3.

Caffeine, 1,3,7-trimethylxanthine, is a central nervous stimulant which occurs as a white powder or white glistening needles.

Aspirin is benzoic acid, 2-(acetyloxy)-, with an empirical formula of C9H8O4.


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