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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Chlorambucil



DESCRIPTION

LEUKERAN (chlorambucil) was first synthesized by Everett et al. It is a bifunctional alkylating agent of the nitrogen mustard type that has been found active against selected human neoplastic diseases. Chlorambucil is known chemically as 4-[bis(2chlorethyl)amino]benzenebutanoic acid. Chlorambucil hydrolyzes in water and has a pKa of 5.8.

LEUKERAN (chlorambucil) is available in tablet form for oral administration. Each sugar-coated tablet contains 2 mg chlorambucil and the inactive ingredients acacia, corn and wheat starch, lactose, magnesium stearate, pharmaceutical glaze, polysorbate 60, sucrose, and talc. Printed with edible black ink.





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