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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (C's) » Cyclobenzaprine



DESCRIPTION

Cyclobenzaprine HCl is a white, crystalline tricyclic amine salt with the empirical formula C20H21N·HCl and a molecular weight of 311.9. It has a melting point of 217°C, and a pKa of 8.47 at 25° C. It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents. If aqueous solutions are made alkaline, the free base separates. Cyclobenzaprine HCl is designated chemically as 3-(5H-dibenzo[a,d] cyclohepten-5-ylidene)-N, N-dimethyl-1-propanamine hydrochloride.

Cyclobenzaprine HCl is supplied as 10 mg tablets for oral administration. Inactive Ingredients: Hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxide, lactose, magnesium stearate, starch, and titanium dioxide.

CATEGORIES, BRAND NAMES

CATEGORIES: Spasm, skeletal muscle; Pregnancy Category B; FDA Approved 1977 Aug; Top 200 Drugs

FDA Drug Classes: Skeletal Muscle Hyperactivity

BRAND NAMES:



BRAND NAMES: Benzamin; Flexeril; Flexiban; Tensodox; Yurelax
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Benzamin (Korea)
Flexiban (Italy; Portugal)
Tensodox (Peru)
Yurelax (Spain)





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