LyophilizedCYTOXAN (cyclophosphamide for injection,
CYTOXAN Tablets (cyclophosphamide tablets, USP)
Lyophilized CYTOXAN (cyclophosphamide for injection, USP)
is a sterile white lyophilized cake, or partially broken cake, containing
75 mg mannitol per 100 mg cyclophosphamide (anhydrous).
CYTOXAN Tablets are for oral use and contain 25 mg or 50 mg cyclophosphamide
Inactive ingredients in CYTOXAN tablets are: acacia, FD&C Blue No.1,
D&C Yellow No.10 Aluminum Lake, lactose, magnesium stearate, starch, stearic
acid and talc.
Cyclophosphamide is a synthetic antineoplastic drug chemically related
to the nitrogen mustards. Cyclophosphamide is a white crystalline powder
with the molecular formula C7H15C12N2O2PH2O
and a molecular weight of 279.1. The chemical name for cyclophosphamide
is 2-[bis(2-chloroethyl)amino] tetrahydro-2H-13,2-oxazaphosphorine 2-oxide
monohydrate. Cyclophosphamide is soluble in water, saline, or ethanol.