DESCRIPTION
DesOwen® Cream 0.05%, Ointment 0.05%, and Lotion 0.05% contain
desonide (Pregna-1,4-diene-3,20-dione,11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,
(11b,16a-)
a synthetic nonfluorinated
corticosteroid
for topical dermatologic
use. The corticosteroids constitute a class
of primarily synthetic
steroids used topically as anti-inflammatory and antipruritic
agents.
Chemically, desonide is C24H32O6.
Desonide has the molecular weight
of 416.51. It is a white
to off white odorless powder
which is soluble in
methanol and practically
insoluble in water.
Each gram of DesOwen Cream
contains 0.5 mg of desonide
in a base of purified water,
emulsifying wax, propylene glycol, stearic acid, isopropyl palmitate,
synthetic beeswax,
polysorbate 60, potassium
sorbate, sorbic acid, propyl
gallate, citric acid, and sodium
hydroxide.
Each gram of DesOwen Ointment
contains 0.5 mg of desonide
in a base of mineral
oil and polyethylene.
Each gram of DesOwen Lotion
contains 0.5 mg of desonide
in a base of sodium lauryl
sulfate, light mineral
oil, cetyl alcohol, stearyl alcohol, propylene glycol, methylparaben,
propylparaben, sorbitan monostearate, glyceryl stearate
SE, edetate sodium and
purified water. May contain citric acid and/or sodium
hydroxide for pH
adjustment.