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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (D's) » Dexfenfluramine (FDA Removed From US Market 9/15/97)



DESCRIPTION

Redux (dexfenfluramine hydrochloride capsules), an anti-obesity drug, is a serotonin reuptake inhibitor and releasing agent. Redux is available for oral administration in white, opaque, hard-gelatin capsules. The active ingredient is dexfenfluramine hydrochloride. Each capsule contains 15 mg dexfenfluramine hydrochloride. Inactive ingredients include: lactose, gelatin capsule, corn starch, microcrystalline cellulose, talc, titanium dioxide, magnesium stearate, colloidal silicon dioxide, and edible ink.

Dexfenfluramine hydrochloride, a white to off-white crystalline powder, is designated chemically as (S)-N-ethyl-alpha-methyl-3-(trifluoromethyl) benzeneethanamine hydrochloride and has a molecular weight of 267.7. Its empirical formula is C12H16F3N·HCl. Dexfenfluramine is freely soluble in water, alcohol, chloroform, and methanol The pKa of dexfenfluramine hydrochloride is 10.

CATEGORIES, BRAND NAMES

CATEGORIES: Amphetamines; Anorexients/CNS Stimulants; Appetite Suppressants; Central Nervous System Agents; Obesity; Psychostimulants; Respiratory/Cerebral Stimulant; Weight Loss; FDA Approved 1996 May

BRAND NAMES: Adifax; Diomeride; Dipondal; Glypolix; Isomeride; Isomerin; Obesine; Redux; Siran
(Foreign brand names outside U.S. in italics)





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