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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (E's) » Erythromycin



DESCRIPTION

Erythromycin is produced by a strain of Saccaropolyspora erythraea (formerlyStreptomyces erythraeus) and belongs to the macrolide group of antibiotics. It is basic and readily forms salts with acids but it is the base which is microbiologically active. Chemically, erythromicin is C37H67NO13.

The chemical name for Erythromycin is (3R*, 4S*, 5S*, 6R*, 7R*, 9R*, 11R*, 12R*, 13S*, 14R*)-4-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L- ribo- hexopyranosyl) -oxy) -14- ethyl-7,12,13- trihydroxy - 3,5,7,9,11,13-hexa methyl-6- ((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo- hexopyran osyl)oxy)oxacyclotetradecane-2,10-dione.

The base is white to off-white crystals or powder slightly soluble in water, soluble in alcohol, in chloroform, and in ether. Erythromycin delayed-release tablets are specially enteric-coated to protect the contents from the inactivating effects of gastric acidity and to permit efficient absorption of the antibiotic in the small intesting.

Erythromycin Delayed-Release Capsules: Erythromycin has the molecular weight of 733.94. The base is white to off-white crystals or powder slightly soluble in water, soluble in alcohol, in chloroform, and in ether. It is odorless or practically odorless. Erythromycin delayed-release tablets are specially enteric-coated to protect the contents from the inactivating effects of gastric acidity and to permit efficient absorption of the antibiotic in the small intestine.

Erythromycin Delayed-Release Capsules contain enteric-coated pellets of erythromycin base for oral administration. Each Erythromycin delayed-release capsule contains 250 milligrams of erythromycin base. Also Contains: Croscarmellose sodium, nonpareil seeds; povidone: FD&C yellow no. 6 aluminum lake and other ingredients. The capsule shell contains gelatin, titanium dioxide; FD&C yellow no. 6.

Topical: Erythromycin topical solution contains 20 mg of erythromycin base in a vehicle consisting of alcohol (66%), propylene glycol, and citric acid to adjust pH.

Pledgets: Each ml of expressible liquid contains 20 mg erythromycin in a base of alcohol (68.5%) (denatured with tert-butyl alcohol and denatonium benzoate), propylene glycol and citric acid to adjust pH. Each pledget is filled to contain 0.8 mL of erythromycin topical solution.

CATEGORIES, BRAND NAMES

CATEGORIES: Acne vulgaris; Amebiasis, intestinal; Conjunctivitis, infectious; Diphtheria; Endocarditis, prevention; Erythrasma; Infection, endocervical; Infection, gynecologic; Infection, lower respiratory tract; Infection, ophthalmic; Infection, rectal; Infection, skin and skin structures; Infection, upper respiratory tract; Infection, urethra; Legionnaires' disease; Pelvic inflammatory disease; Pertussis; Pneumonia; Rheumatic fever, prophylaxis; Syphilis; Pregnancy Category B; FDA Approved 1964 Jun; Top 200 Drugs; WHO Formulary

FDA Drug Classes: Acne Products; Macrolides; Ocular Anti-Infective; Topical Anti-Infectives

BRAND NAMES:

BRAND NAMES: A T S; Abboticin; Abboticine; Abomacetin; Acneryne; Acnesol; Aknederm Ery Gel; Akne-Mycin; Aknemycin; C-Solve-2; Del-Mycin; Deripil; Dumotrycin; E-Base; E-Mycin; ETS; Emgel; Emu-V; Emu-Ve; Emuvin; Emycin; Endoeritrin; Erimycin-T; Erisone; Eritomicina; Eritrocina; Eritromicina; Ermycin; Eros; Eryacne; Eryacnen; Ery-B; Eryc; Eryc-125; Eryc-250; Eryc LD; Erycen; Erycette; Erycin; Erycinum; Eryderm; Erydermer; Ery-Diolan; Erygel; Eryhexal; Erymax; Ery-maxin; Erymed; Erysafe; Ery-Tab; Erytab; Erythra-Derm; Erythrocin; Erythroderm; Erythromid; Erythromycin; Erythro-Teva; Erytop; Erytrarco; Erytrociclin; Iloticina; Ilotycin; Ilotycin T.S.; Inderm Gel; Latotryd; Lederpax; Mephamycin; Mercina; Monomycin; Oftamolets; Oftalmolosa Cusi Eritromicina; PCE; Paediathrocin; Pantoderm; Pantodrin; Pantomicina; Primacine; Proterytrin; Retcin; Robimycin; Romycin; Sans-acne; Sansac; Skid Gel E; Staticin; Stiemycin; Stimycine; T-Stat
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Abboticin (Denmark; Finland; Norway; Sweden)
Abboticine (Denmark; Finland; Norway; Sweden)
Abomacetin (Japan)
Acneryne (Belgium)
Acnesol (India)
Akne Cordes Losung (Germany)
Aknederm Ery Gel (Germany)
Aknemycin (Austria; Belgium; Germany)
Derimer (Korea)
Deripil (Spain)
E-Mycin (Bahrain; Canada; Cyprus; Egypt; Hong-Kong; India; Iran; Iraq; Israel; Israel; Jordan; Kuwait; Lebanon; Libya; Malaysia; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Emu-V (Australia; New-Zealand; New-Zealand; South-Africa)
Emu-Ve (Argentina)
Emuvin (Austria)
Emycin (Korea)
Erecin (Korea)
Erimycin-T (Thailand)
Eritrocina (Italy)
Eritromicina (Colombia)
Ermycin (Bahamas; Bahrain; Barbados; Belize; Bermuda; Curacao; Cyprus; Egypt; Guyana; Iran; Iraq; Israel; Jamaica; Jordan; Kuwait; Lebanon; Libya; Netherland-Antilles; Oman; Puerto-Rico; Qatar; Republic-Of-Yemen; Saudi-Arabia; Surinam; Syria; Trinidad; United-Arab-Emirates)
Eros (Indonesia)
Eryacne (Australia)
Eryacnen (Ecuador)
Ery-B (Taiwan)
Eryc (Australia; Bahamas; Barbados; Belize; Bermuda; Bulgaria; Curacao; Czech-Republic; Guyana; Hong-Kong; Hungary; Indonesia; Israel; Jamaica; Korea; Netherland-Antilles; Netherlands; New-Zealand; New-Zealand; Puerto-Rico; Russia; Surinam; Trinidad)
Eryc-125 (Canada)
Eryc-250 (Canada)
Erycen (England; Ireland)
Erycin (Denmark; Philippines)
Erycinum (Austria)
Eryderm (Bahrain; Belgium; Cyprus; Egypt; Iran; Iraq; Israel; Israel; Jordan; Kuwait; Lebanon; Libya; Malaysia; Mexico; Netherlands; Oman; Qatar; Republic-Of-Yemen; Russia; Saudi-Arabia; South-Africa; Switzerland; Syria; United-Arab-Emirates)
Erydermer (Germany)
Ery-Diolan (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Eryhexal (Germany; Russia)
Erymax (Belgium; Benin; Burkina-Faso; Ethiopia; Finland; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Norway; Philippines; Senegal; Seychelles; Sierra-Leone; South-Africa; South-Africa; Sudan; Sweden; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Ery-maxin (Austria)
Erymed (Indonesia)
Erysafe (India)
Ery-Tab (Bahamas; Barbados; Belize; Bermuda; Curacao; Guyana; Jamaica; Netherland-Antilles; Puerto-Rico; Surinam; Thailand; Trinidad)
Erytab (Israel)
Erythrocin (Hong-Kong; India; Turkey)
Erythroderm (Israel)
Erythromid (Canada; Ireland; South-Africa)
Erythromycin (Denmark; Hungary; India)
Erythro-Teva (Israel)
Erytop (Germany)
Erytrarco (Switzerland)
Erytrociclin (Italy)
Iloticina (Colombia)
Ilotycin T.S. (South-Africa)
Inderm Gel (Germany)
Latotryd (Mexico)
Lederpax (Mexico)
Mephamycin (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Monomycin (Germany)
Oftamolets (Argentina)
Oftalmolosa Cusi Eritromicina (Spain)
Paediathrocin (Germany)
Pantoderm (Colombia)
Pantodrin (Spain)
Pantomicina (Argentina; Ecuador)
Pharyngocin (Germany)
Primacine (Indonesia)
Robimycin (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Sans-acne (Canada; Mexico)
Skid Gel E (Germany)
Stiemicyn (Mexico)
Stiemycin (Benin; Burkina-Faso; England; Ethiopia; Gambia; Ghana; Guinea; Hong-Kong; Ivory-Coast; Kenya; Korea; Liberia; Malawi; Malaysia; Mali; Mauritania; Mauritius; Morocco; New-Zealand; Niger; Nigeria; Philippines; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Thailand; Tunia; Uganda; Zambia; Zimbabwe)
Stimycine (Belgium; France)

COST OF THERAPY: $8.12 (Skin Infections; E-Mycin Tablet; 250 mg; 4/day; 7 days)





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