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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (F's) » Furosemide



WARNING

Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose and dose schedule must be adjusted to the individual patient's needs. (See DOSAGE AND ADMINISTRATION.)

DESCRIPTION

Tablets: Lasix is a diuretic which is an anthranilic acid derivative. Lasix for oral administration contains furosemide as the active ingredient and the following inactive ingredients: lactose, magnesium stearate, starch, and talc. Chemically, it is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. Furosemide is available as white tablets for oral administration in dosage strengths of 20, 40 and 80 mg.

Furosemide is a white to off-white odorless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids.

The CAS Registry Number is 54-31-9.

Injection: Lasix injection is composed of 4-chloro-N-furfuryl-5- sulfamoylanthranilic acid, sodium chloride for isotonicity and sodium hydroxide to adjust pH.

Lasix injection 10 mg/ml is a sterile, non-pyrogenic solution in ampules, disposable syringes and single dose vials for intravenous and intramuscular injection.

Oral Solution: Lasix oral solution contains furosemide as the active ingredient and the following inactive ingredients: alcohol 11.5%, D&C yellow #10, FD&C yellow #6 as color additives, flavors, glycerin, parabens, purified water, sorbitol; sodium hydroxide added to adjust pH. Lasix oral solution 10 mg/ml is an orange flavored liquid for oral administration.

CATEGORIES, BRAND NAMES

CATEGORIES: Edema, pulmonary, adjunct; Edema, secondary to heart failure; Edema, secondary to hepatic cirrhosis; Edema, secondary to renal dysfunction; Hypertension, essential; Pregnancy Category C; FDA Approved 1968 Mar; Top 200 Drugs; WHO Formulary

FDA Drug Classes: Antihypertensives; Diuretics

BRAND NAMES:

BRAND NAMES: Aldic; Aluzine; Anfuramaide; Apo-Frusemide; Apo-Furosemide; Aquarid; Aquamide; Aquasin; Arasemide; Bioretic; Cetasix; Dirine; Disemide; Diural; Diuresal; Diurin; Diurolasa; Diusemide; Diusil; Dranex; Dryptal; Durafurid; Edenol; Errolon; Eutensin; Fluidrol; Franyl; Frumex; Furmid; Frusedan; Frusema; Frusemide; Frusetic; Frusid; Furanthril; Furanturil; Furetic; Furex; Furix; Frumide; Furo-Basan; Furocot; Furodiurol; Furomen; Furomex; Furomide M.D.; Furo-Puren; Furorese; Furosan; Furosix; Furoter; Furovite; Fusid; Golan; Hissuflux; Hydrex; Hydro; Impugan; Kofuzon; Kutrix; Lasemid; Lasiletten; Lasilix; Lasix; Lasix Retard; Laxur; Liside; Marsemide; Naclex; Nadis; Nelsix; Nephron; Odemase; Odemex; Oedemex; Promedes; Promide; Radisemide; Radonna; Retep; Salinex; Salurid; Seguril; Selectofur; Trofurit; Uremide; Urenil; Uresix; Urex; Urex-M; Urian; Uridon; Yidoli; Zafurida
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Aldic (Thailand)
Anfuramaide (Taiwan)
Apo-Frusemide (New-Zealand)
Apo-Furosemide (Canada)
Aquarid (South-Africa)
Arasemide (Japan)
Cetasix (Indonesia)
Dirine (Malaysia)
Diural (Denmark; Norway; Sweden; Switzerland)
Diuresal (Bahamas; Bahrain; Barbados; Belize; Benin; Bermuda; Burkina-Faso; Curacao; Cyprus; Egypt; Ethiopia; Gambia; Ghana; Guinea; Guyana; Iran; Iraq; Israel; Ivory-Coast; Jamaica; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Netherland-Antilles; Niger; Nigeria; Oman; Puerto-Rico; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Surinam; Syria; Taiwan; Tanzania; Trinidad; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Diurin (New-Zealand)
Diurolasa (Spain)
Diusemide (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Dryptal (England; Hong-Kong; Ireland)
Durafurid (Germany)
Edenol (Mexico)
Errolon (Argentina)
Eutensin (Japan)
Franyl (Japan)
Furmid (Malaysia)
Frusedan (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Frusema (Philippines)
Frusemide (Hong-Kong)
Frusid (New-Zealand)
Furanthril (Czech-Republic)
Furanturil (Bulgaria)
Furetic (Thailand)
Furix (Korea; Norway; Sweden)
Furo-Basan (Switzerland)
Furomen (Finland)
Furomex (Czech-Republic)
Furo-Puren (Germany)
Furorese (Germany)
Furosix (Indonesia)
Furovite (Israel)
Fusid (Germany; Israel)
Hissuflux (Colombia)
Hydrex (South-Africa)
Impugan (Denmark; Indonesia; Sweden; Switzerland; Thailand)
Kofuzon (Taiwan)
Kutrix (Japan)
Lasiletten (Netherlands)
Lasilix (France; Morocco)
Lasix Retard (Denmark; Netherlands; Norway; Portugal; Sweden)
Laxur (Chile)
Marsemide (Philippines)
Naclex (Indonesia)
Nephron (Argentina)
Odemex (Costa-Rica; Dominican-Republic; Ecuador; El-Salvador; Guatemala; Honduras; Nicaragua; Panama)
Oedemex (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Switzerland; Syria; United-Arab-Emirates)
Promedes (Japan)
Radisemide (Bahrain; Benin; Burkina-Faso; Cyprus; Egypt; Ethiopia; Gambia; Ghana; Guinea; Iran; Iraq; Israel; Ivory-Coast; Jordan; Kenya; Kuwait; Lebanon; Liberia; Libya; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Senegal; Seychelles; Sierra-Leone; South-Africa; Sudan; Syria; Tanzania; Tunia; Uganda; United-Arab-Emirates; Zambia; Zimbabwe)
Retep (Argentina)
Salinex (India)
Seguril (Spain)
Selectofur (Mexico)
Uremide (Australia; New-Zealand)
Urenil (Japan)
Uresix (Indonesia)
Urex (Australia; Hong-Kong; Japan; New-Zealand)
Urex-M (Australia; New-Zealand)
Zafurida (Mexico)

COST OF THERAPY: $204.40 (Hypertension; Lasix Tablet; 40 mg; 2/day; 365 days)

HCFA JCODE(S): J1940 up to 20 mg IM, IV





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