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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (G's) » Guaifenesin and Pseudoephedrine


Please note the brand names, Deconsal II Tablets and Deconsal L.A. Tablets have been used in this monograph where noted to avoid confusion.

Deconsal II: Each scored, dark blue Deconsal II Tablet provides 60 mg pseudoephedrine hydrochloride and 600 mg guaifenesin in a sustained-release formulation intended for oral administration. Inactive ingredients: Stearic acid, dibasic calcium phosphate, FD&C Blue #1 Lake, sodium lauryl sulfate, ethylcellulose, magnesium stearate.

Deconsal L.A.: Each scored, light blue Deconsal L.A. Tablet provides 120 mg pseudoephedrine hydrochloride and 400 mg guaifenesin in a sustained-release formulation intended for oral administration.

Pseudoephedrine hydrochloride is a nasal decongestant. Chemically, it is [S-(R*,R*)]-alpha-[1-(methylamino)ethyl]-, benzenemethanol hydrochloride and has the following formula: C10H15NO°HCl and a molecular weight of 201.70.

Guaifenesin is an expectorant. Chemically it is, 3-(2-methoxyphenoxy)-1,2 propanediol and has the following chemical formula: C10H14O4 and a molecular weight of 198.22.


CATEGORIES: Bronchitis; Cold, Common; Congestion, Nasal; Cough; Sinusitis; DEA Class CIII; FDA Pre 1938 Drugs; Pregnancy Category C

FDA Drug Class: Antitussives/Expectorants/Mucolytics; Cold Remedies; Nasal Decongestants

BRAND NAMES: Cophene-S; Cophene-Xp; Deconamine Cx; Detussin; Duratuss HD; Entuss-D; Hydro-Coff; Hyphed; Hytussin; Kg-Tuss Hd; Med-Hist; Pancof Xp; Poly-Tussin Xp; Protuss-D; Spantuss Hd; Src Expectorant; Tussadur-Hd; Tussafin; Tussend; Tussgen; Vanacon; Vanex

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