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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (H's) » Hydrochlorothiazide and Triamterene


Each Dyazide capsule for oral use, with opaque red cap and opaque white body, contains hydrochlorothiazide 25 mg and triamterene 37.5 mg, and is imprinted with the product name DYAZIDE and SB. Hydrochlorothiazide is a diuretic/antihypertensive agent and triamterene is an antikaliuretic agent.

Hydrochlorothiazide is slightly soluble in water. It is soluble in dilute ammonia, dilute aqueous sodium hydroxide and dimethylformamide. It is sparingly soluble in methanol.

Hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide 1,1-dioxide.

At 50°C, triamterene is practically insoluble in water (less than 0.1%). It is soluble in formic acid, sparingly soluble in methoxyethanol and very slightly soluble in alcohol.

Triamterene is 2, 4, 7-triamino-6-phenylpteridine.

Inactive ingredients consist of benzyl alcohol, cetylpyridinium chloride, D&C red no. 33, FD&C yellow no. 6, gelatin, glycine, lactose, magnesium stearate, microcrystalline cellulose, povidone, polysorbate 80, sodium starch glycolate, titanium dioxide, and trace amounts of other inactive ingredients.

Dyazide capsules meet Drug Release Test 3 as published in the USP 23 monograph for triamterene and hydrochlorothiazide capsules.


CATEGORIES: Edema; Hypertension, essential; Pregnancy Category C; FDA Approval Pre 1982; Top 200 Drugs

FDA Drug Classes: Antihypertensives; Diuretics


BRAND NAMES: Anjal; Apo-triazide; Dazid; Dinazide; Dyazide; Dyberzide; Dytenzide; Dytide H; Esiteren; Hydrene; Loretic; Maxzide; Renezide; Slimin; Triamizide; Triazide; Trizid; Turfa
(Foreign Brand names outside U.S. in italics)

Anjal (Taiwan)
Apo-triazide (Canada)
Dazid (Taiwan)
Dinazide (Thailand)
Dyberzide (Greece)
Dytenzide (Belgium; Netherlands)
Dytide H (Austria; Germany)
Esiteren (Germany)
Hydrene (Australia; New-Zealand)
Renezide (South-Africa)
Triamizide (New-Zealand; Taiwan)
Triazide (Taiwan)
Trizid (Hong-Kong; New-Zealand)
Turfa (Germany)

COST OF THERAPY: $350.40 (Hypertension; Dyazide Tablet; 25 mg;37.5 mg; 2/day; 365 days)

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