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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (i's) » Indomethacin


Indomethacin cannot be considered a simple analgesic and should not be used in conditions other than those recommended under INDICATIONS AND USAGE. Indomethacin is available in 25 and 50 mg capsules for oral administration.

Inactive ingredients include: corn starch, D& C Red No.7 calcium lake, D& C Yellow No.10, FD& C Green No.3, FD& C Blue No.1 aluminum lake, FD& C Blue No.2 aluminum lake, gelatin, lactose monohydrate, lecithin, silicon dioxide, sodium lauryl sulfate, stearic acid, synthetic black iron oxide and titanium dioxide.

Indomethacin is a nonsteroidal anti-inflammatory indole derivative designated chemically as 1-(4-chlorobenzoyl)-5-methoxy- 2-methyl-1-H-indole-3-acetic acid. Indomethacin is practically insoluble in water and sparingly soluble in alcohol. It has a pKa of 4.5 and is stable in neutral or slightly acidic media and decomposes in strong alkali.

The chemical formula is: C19H16ClNO4 and its molecular weight is 357.79.

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