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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (M's) » Metformin


Metformin HCl is an oral antihyperglycemic drug used in the management of non-insulin-dependent diabetes mellitus (NIDDM). Metformin HCl (N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to the oral sulfonylureas.

Metformin HCl is a white to off-white crystalline compound with a molecular formula of C4H11N5HCl and a molecular weight of 165.63. Metformin HCl is freely soluble in water and is practically insoluble in acetone, ether and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin HCl is 6.68.

Metformin HCl tablets contain 500 mg and 850 mg of metformin HCl. In addition, each tablet contains the following inactive ingredients: povidone, magnesium stearate and hydroxypropyl methylcellulose (hypromellose) coating.


CATEGORIES: Diabetes mellitus; Pregnancy Category C; FDA Class 1P ("Priority Review"); FDA Approved 1994 Dec; Top 200 Drugs

FDA Drug Classes: Blood Glucose Regulators


BRAND NAMES: Apophage; Benofomin; Dabex; Denkaform; Dextin; Diabetmin; Diabex; Diaformin; Diformin; Diformin Retard; Dimefor; Fornidd; Geamet; Glucaminol; Glucofago; Glucomet; Glucomine; Glucoform; Glucomin; Gluconil; Glucophage; Glucophage 850; Glucophage Forte; Glucophage-Mite; Glucophage Retard; Gludepatic; Glufor; Gluformin; Glumeformin; Glumin; Glupermin; Glyciphage; Glycon; Metforal; Metomin; Miformin; Orabet; Siamformet; Walaphage
(Foreign Brand names outside U.S. in italics)

Apophage (Israel)
Benofomin (Indonesia)
Dabex (Mexico)
Denkaform (Philippines)
Dextin (South-Africa)
Diabetmin (Malaysia)
Diabex (Australia; Indonesia)
Diaformin (Australia; Hong-Kong; Taiwan)
Diformin (Finland)
Diformin Retard (Finland)
Dimefor (Costa-Rica; El-Salvador; Guatemala; Honduras; Mexico; Nicaragua; Panama)
Fornidd (Philippines)
Geamet (Benin; Burkina-Faso; Ethiopia; Gambia; Ghana; Guinea; Ivory-Coast; Kenya; Liberia; Malawi; Mali; Mauritania; Mauritius; Morocco; Niger; Nigeria; Senegal; Seychelles; Sierra-Leone; Sudan; Tanzania; Tunia; Uganda; Zambia; Zimbabwe)
Glucaminol (Colombia)
Glucofago (Peru)
Glucomet (Australia; New-Zealand; Thailand)
Glucomine (Taiwan)
Glucoform (Philippines)
Glucomin (Israel)
Gluconil (Korea)
Glucophage 850 (Thailand)
Glucophage Forte (Czech-Republic; Mexico; Netherlands; Philippines; South-Africa)
Glucophage-Mite (Germany)
Glucophage Retard (Germany; Israel)
Gludepatic (Indonesia)
Glufor (Israel)
Gluformin (Thailand)
Glumeformin (Korea)
Glumin (Indonesia)
Glupermin (Korea)
Glyciphage (India)
Glycon (Canada)
Metforal (Bahrain; Cyprus; Egypt; Iran; Iraq; Italy; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Metomin (New-Zealand)
Miformin (Thailand)
Orabet (Austria; Bahrain; Cyprus; Denmark; Egypt; England; Iran; Iraq; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Siamformet (Thailand)
Walaphage (India)

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