Methyclothiazide, a diuretic-antihypertensive agent, is a member of the
benzothiadiazine (thiazide) class of drugs. It is an analogue of hydrochlorothiazide
and occurs as a white to practically white crystalline powder which is
basically odorless. Methyclothiazide is very slightly soluble in water
and chloroform, and slightly soluble in alcohol. Chemically, methyclothiazide
is represented as 6-chloro-3(chloromethyl)-3, 4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide
It has the following molecular formula C9H11Cl2N3O4S2
with a molecular weight of 360.23.
Each methyclothiazide tablet for oral administration contains 5 mg methyclothiazide
and the following inactive ingredients: colloidal silicon dioxide, magnesium
stearate, microcrystalline cellulose, pregelatinized starch, sodium lauryl
sulfate, sodium starch glycolate and FD&C Blue #1.