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You are here: Home » eGM Resources » Health Information & Resources Portal|Home » RX Drug List (listed alphabetically) » Drug Reference (M's) » Methylprednisolone



DESCRIPTION

Methylprednisolone is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Methylprednisolone occurs as a white to practically white, odorless, crystalline powder. It is sparingly soluble in alcohol, in dioxane, and in methanol, slightly soluble in acetone, and in chloroform, and very slightly soluble in ether. It is practically insoluble in water.

The chemical name for methylprednisolone is pregna-1,4-diene-3,20 -dione, 11,17,21-trihydroxy-6-methyl-,(6a, 11b)- and the molecular weight is 374.48.

Each Medrol tablet for oral administration contains 2 mg, 4 mg, 8 mg, 16 mg, 24 mg or 32 mg of methylprednisolone.

Medrol Inactive Ingredients

2 mg: Calcium stearate, corn starch, erythrosine sodium, lactose, mineral oil, sorbic acid, sucrose.
4 and 16 mg: Calcium stearate, corn starch, lactose, mineral oil, sorbic acid, sucrose.
8 and 32 mg: Calcium stearate, corn starch, FD&C yellow no.6, lactose, mineral oil, sorbic acid, sucrose.
24 mg: Calcium stearate, corn starch, FD&C yellow no.5, lactose, mineral oil, sorbic acid, sucrose.

CATEGORIES, BRAND NAMES

CATEGORIES: Adrenocortical insufficiency; Anemia, acquired hemolytic; Anemia, congenital hypoplastic; Anemia, erythroblastopenia; Ankylosing spondylitis; Arthritis, gouty; Arthritis, post-traumatic; Arthritis, psoriatic; Arthritis, rheumatoid; Asthma; Berylliosis; Bursitis; Carditis, rheumatic; Chorioretinitis; Choroiditis; Colitis, ulcerative; Conjunctivitis, allergic; Dermatitis herpetiformis, bullous; Dermatitis, atopic; Dermatitis, contact; Dermatitis, exfoliative; Dermatitis, seborrheic; Dermatomyositis, systemic; Enteritis, regional; Epicondylitis; Erythema multiforme; Herpes zoster ophthalmicus; Hypercalcemia, secondary to neoplasia; Hypersensitivity reactions; Inflammation, anterior segment, ophthalmic; Inflammation, ophthalmic; Iridocyclitis; Iritis; Irritable bowel syndrome; Keratitis; Leukemia; Loffler's syndrome; Lupus erythematosus, systemic; Lymphoma; Meningitis, tuberculous; Multiple sclerosis; Mycosis fungoides; Nephrotic syndrome; Neuritis, optic; Ophthalmia, sympathetic; Pemphigus; Pneumonitis, aspiration; Polymyositis; Psoriasis; Rhinitis, perennial allergic; Rhinitis, seasonal allergic; Sarcoidosis; Serum sickness; Stevens-Johnson syndrome; Synovitis, secondary to osteoarthritis; Tenosynovitis; Thrombocytopenia, secondary; Thyroiditis, nonsuppurative; Trichinosis; Tuberculosis, disseminated; Tuberculosis, fulminating; Tuberculosis, meningitis; Ulcer, allergic corneal marginal; Uveitis; FDA Approved 1978 Apr; Top 200 Drugs

FDA Drug Classes: Corticosteroids; Antiarthritics

BRAND NAMES:

BRAND NAMES: Esametone; Firmacort; Medlone 21; Mednin; Medrate; Medrol; Medixon; Medrone; Metrocort; Metypred; Reactenol; Sieropresol; Solomet; Summicort; Urbason; Urbason Retard
(Foreign Brand names outside U.S. in italics)

FOREIGN BRAND AVAILABILITY:
Esametone (Italy)
Firmacort (Italy)
Mednin (Taiwan)
Medrate (Germany)
Medixon (Indonesia)
Medrone (England; Ireland)
Metypred (Bahrain; Cyprus; Egypt; Iran; Iraq; Israel; Jordan; Kuwait; Lebanon; Libya; Oman; Qatar; Republic-Of-Yemen; Saudi-Arabia; Syria; United-Arab-Emirates)
Solomet (Finland)
Urbason (Austria; Bulgaria; Czech-Republic; Germany; Netherlands; Spain; Switzerland)
Urbason Retard (Belgium; Bulgaria; Germany; Italy)

HCFA JCODE(S): J7509 per 4 mg ORAL

COST OF THERAPY: $302.95 (Asthma; Medrol Tablet; 4 mg; 1/day; 365 days)





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